Breast cancer prevention by natural products

Project Description: We are currently evaluating natural products as a preventive agent of breast cancer targeting epigenome. We have developed an in vitro cell culture model and evaluate the potential of wild Yam root extract as a modulator of human breast cancer cell lines.

Desired Student Qualifications: Biology based training is necessary

Project Timeline: Depends upon the project

Duties of Student Researcher: Maintenance of cell lines, treatment of cells, extraction of nucleic acids, run qPCR and western blot,enzyme analysis.

Last Updated on 2014-09-05 10:03:19

Ethanol and Parkinson's disease

Project Description: We are evaluating toxic potential of alcohol in embryo development using Japanese medaka fish as the experimental model. In the USA about 10% of the women are drinking alcohol that affects embryo development. We predict that the several of the neurobehavioral disorders including Parkinson's disease, Alzheimer's disease that are found in person over 60 is due to their exposure to ethanol during fetal lifet. At present we are characterizing several genes that are responsible for both Parkinson's disease and FASD and their response to ethanol exposure.

Desired Student Qualifications: Students with Biology background.

Project Timeline: 2015-2020

Duties of Student Researcher: Student is responsible for fish maintenance, dissecting fish brain, Immunohistochemical and biochemical characterization of the target genes essential for FASD/Parkinson's disease. Analysis of fish behavior.

Last Updated on 2015-09-30 12:19:45