Faculty Profile

Deborah Gochfeld
Principal Scientist of National Center for Natural Products Research
Phone Number: (662)915-6769
Email: gochfeld@olemiss.edu
http://www.pharmacy.olemiss.edu/php/sopquery3.php?id=59

Key Words: chemical ecology, marine invertebrates, coral reef ecology, physiological ecology, marine natural products, focusing on the roles of secondary metabolites, host-pathogen interactions, predator-prey interactions, environmental stress, climate change

Research Description: My research focuses on physiological and ecological adaptations of marine organisms to natural and human-induced stressors in the environment and on the ecological functions of marine natural products, particularly on the roles of secondary metabolites in host-pathogen and predator-prey interactions.

Honors Theses:

Reilly, Mackenzie (2020) Variability in Antibacterial Activity in the Caribbean Sponge Amphimedon compressa (full text)

Sisson, Coleman (2019) Geographical Variability in Antibacterial Chemical Defenses of the Caribbean Sponge Xestospongia muta (full text)

Cole, Carley Elizabeth (2018) Effects of Predation on the Biochemical Constituents of the Bleached Soft Coral Sinularia polydactyla (full text)

Vickers, Mafie Claire (2017) Impacts of Aplysina Red Band Syndrome on Secondary Metabolite Profiles and Antibacterial Activity of the Caribbean Sponge Genus Aplysina. (full text)

Criddle, Sarah L (2017) Biochemical Variation in Caribbean Sponges of the Genus Aplysina. (full text)

Stockton, Savannah (2016) Variability in Antibacterial Chemical Defenses in Caribbean Sponges of the Genus Aplysina. (full text)

Pappas, Katerina Elaine (2010) "Effects of Bleaching and Disease Stress on Antimicrobial Chemical Defenses in Corals."

Available Research Projects:

Metabolic responses to disease in marine sponges

Project Description: Marine sponges on coral reefs are increasingly susceptible to diseases, some of which are likely caused by bacterial pathogens. Sponges are very primitive animals, but basic physiological principles apply, including potential redistribution of energetic molecules when exposed to stress, such as disease. This project will evaluate the distribution of biochemical molecules (proteins, lipids, carbohydrates) in a Caribbean sponge species known to be susceptible to disease and will compare the distribution of these molecules in healthy vs. diseased sponges from different sites in the Caribbean and from different morphotypes. The project involves laboratory research in chemistry/biochemistry with background information on marine ecology, coral reefs stressors, disease ecology and bioenergetics.

Desired Student Qualifications: Introductory biology and chemistry courses, with advanced coursework in biochemistry or chemistry preferred but not essential. Basic laboratory skills preferred. Student will be required to take University Health & Safety courses in Biological and Chemical Safety prior to working in the lab.

Project Timeline: Fall 2016-Summer 2017, possibly longer

Duties of Student Researcher: Dry and weigh frozen sponge samples. Perform protein, lipid and carbohydrate assays using standard assay protocols. Data analysis will also be performed. Basic and advanced chemistry laboratory skills will be used. Once trained, student will work relatively independently, with guidance from two PIs and another Honors student.

Last Updated on 2016-12-07 10:13:27